Nexium ClearMinis 24HR Acid Reducer Heartburn Relief Capsules with Esomeprazole Magnesium contain all the power of Nexium 24HR heartburn medicine in an approximately 38 percent smaller pill that is easy to swallow. Just one Nexium 24HRClearMinis capsule a day provides complete all day, all night protection from heartburn (1). Part of a group of medications called proton pump inhibitors (PPIs), Nexium 24HR capsules contain a delayed release formula with esomeprazole magnesium to block acid at the source, turning your body’s acid pumps from on to off for complete heartburn protection (2). Like other PPIs, Nexium 24HR acid blocker capsules may take from 1 to 4 days to reach full effect, but relief lasts for 24 hours, letting you power through your day and sleep peacefully through the night without heartburn interruptions. This package of Nexium capsules contains a 14-day course of treatment in one convenient storage box. Don't let heartburn pause the moment. Stop acid before it starts with Nexium 24HR, in a clear mini pill. Nexium has reduced the plastic in over 25 million Nexium bottles by 15 percent, which has resulted in a reduction of 31 tons of plastic in the environment annually.