Compare to the active ingredients of Extra Strength Benadryl Itch Stopping Cream. Find relief for painful, uncomfortable itching with Equate Extra Strength Anti-Itch and Skin Protectant Cream. This itch relief cream temporarily relieves most outdoor itches due to bug bites, sunburn and rashes from poison ivy, poison oak or poison sumac. It also provides extra strength, fast pain and itch relief from other minor skin irritations such as minor burns, scrapes and cuts. First Aid anti-itch and skin protectant cream will help to keep you from itching irritated skin. This product contains diphenhydramine hydrochloride 2 percent, a topical analgesic and zinc acetate 0.1 percent, a skin protectant.