Maximum-strength itch relief without a prescription that works fast and lasts for hours while also providing skin with 24-hour moisture. Cortizone 10 Maximum Strength Intensive Moisture Anti-Itch Cream relieves itch fast and lasts for hours. Formulated with maximum-strength hydrocortisone, this anti-itch cream nourishes and hydrates skin while relieving itch with seven moisturizers and three vitamins. Use it on minor skin irritations, rashes, insect bites, and poison ivy and sumac. Cortizone 10 Intensive Moisture Cream provides 24-hour moisture in a fragrance-free and dye-free formula. No wonder it's the No. 1 doctor-recommended anti-itch brand among topical analgesics.